Human Carcinoma Cells Synthesize and Secrete Tenascinin vitro
نویسندگان
چکیده
منابع مشابه
Human eosinophils synthesize and secrete interleukin-6, in vitro.
Using the technique of in situ hybridization, we have shown that resting, unstimulated, human peripheral blood eosinophils, obtained from subjects with greater than 8% eosinophilia, transcribe and translate messenger RNA (mRNA) for interleukin-6 (IL-6). After incubation for 24 hours in culture medium alone, approximately 19% of eosinophils were positive for IL-6 mRNA. This may be a reflection o...
متن کاملHuman Endothelial Cells Synthesize , Process , and Secrete Fibronectin Molecules
Cellular fibronectin (Fn) bearing an alternatively spliced extra type 111 structural repeat (ED1 1 is normally present at low concentrations in blood plasma. The source of this material remains uncertain. In this study, primary cultures of human umbilical vein endothelial cells (HUVEC) labeled with 36S-methionine were observed to synthesize Fn monomers both with and without this segment. Monome...
متن کاملActivated microglial cells synthesize and secrete AGE-albumin
A holy grail of curing neurodegenerative diseases is to identify the main causes and mechanisms underlying neuronal death. Many studies have sought to identify these targets in a wide variety of ways, but a more important task is to identify critical molecular targets and their origins. Potential molecular targets include advanced glycation end products (AGEs) that can promote neuronal cell dea...
متن کاملSertoli cells synthesize and secrete transferrin-like protein.
One of the major proteins secreted by Sertoli cells (Band 3) has a molecular weight on sodium dodecyl sulfate-polyacrylamide gels which corresponds to rat serum transferrin. The preparation of Sertoli cell-secreted proteins contains an iron-binding protein with electrophoretic properties on native polyacrylamide gels similar to serum transferrin. Antibodies against Sertoli cell-secreted protein...
متن کاملCultured human monocytes synthesize and secrete alpha2-macroglobulin
alpha2-Macroglobulin levels in the supernates of cultures of different subpopulations of human peripheral blood mononuclear leukocytes were assayed by a radioimmunoassay. Unfractionated mononuclear leukocytes produced greater amounts of the macroglobulin (4.0 vs. 0.8 ng/10(6) cells) than did subpopulations enriched in T or B+T lymphocytes, by passage through nylon wool or cotton wool columns, r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Cancer Research
سال: 1992
ISSN: 0910-5050
DOI: 10.1111/j.1349-7006.1992.tb02724.x